More than 130 practices in over 115 locations

Palmetto Health-USC Medical Group is the largest multispecialty, clinically integrated medical group providing the broadest range of health care services in the Midlands region.

Transforming Care in our Community


Recent News

Cardiology team helps cheerleader with care needed to save her life

Sarah Beth Sheridan had bad headaches, rapid heartbeats and passing out spells.

Featured Physician

Tips for keeping a healthy smile

James Curtis, DMD, discusses how to keep teeth clean and healthy for World Oral Health Day.

Online Care

Flu? Use SmartExam for quick care online

Get easy, affordable access to a Prisma Health care provider from your mobile device or computer.

More than 850 providers

Along with our 2,200 team members, we offer patients the broadest range of health care services in the Midlands.

Get the Facts

Our affiliate system

Prisma Health is the largest not-for-profit health organization in South Carolina, serving more than 1.2 million patients annually. Our 30,000 team members are dedicated to supporting the health and well-being of you and your family. Palmetto Health-USC Medical Group will be rebranded at a later date and will continue to operate as a joint venture between the Midlands affiliate and the USC School of Medicine.

Our promise is to: Inspire health. Serve with compassion. Be the difference.

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Palmetto Health is becoming Prisma Health. Palmetto Health-USC Medical Group is part of Prisma Health.