Christopher G. Mazoué, MD

Orthopedic Surgery, Sports Medicine
Clinical Associate Professor of Orthopedic Surgery


Christopher G. Mazoué, MD, is a board-certified, fellowship-trained orthopedic surgeon specializing in sports medicine, arthroscopic surgery and the treatment of complex shoulder, elbow and knee injuries at Palmetto Health-USC Orthopedic Center. He serves as department chair and is a clinical associate professor of orthopedic surgery with the University of South Carolina School of Medicine.

Dr. Mazoué attended Cornell University in Ithaca, New York, where he received a bachelor's degree in economics and won an Ivy League championship in football. He received his medical degree from Louisiana State University School of Medicine in New Orleans, where he was elected into the Alpha Omega Alpha (AOA) Honors Medical Society. He then completed his residency in orthopedic surgery at the University of Texas Southwestern Medical Center in Dallas. Following residency, he completed a fellowship in sports medicine at the American Sports Medicine Institute in Birmingham, Alabama, under the guidance of renowned orthopedic surgeons James Andrews, MD, and William Clancy, MD.

With extensive experience caring for athletes at all levels, Dr. Mazoué has treated patients from youth to professional leagues. He provides care for numerous local middle schools, high schools and colleges. He has served as team physician for South Carolina State University, where he was elected into the South Carolina State Athletic Hall of Fame for his service to the university. He has been a team physician for the University of South Carolina Gamecocks for over fifteen years and is a consultant for Coastal Carolina University. He also serves as chairman of the South Carolina Medical Association Medical Aspects of Sports Medicine Committee.

Dr. Mazoué’s clinical expertise includes complex shoulder and elbow surgery, shoulder reconstruction, shoulder replacement and complex knee injuries. This includes arthroscopic shoulder stabilization, arthroscopic rotator cuff repair and superior capsular reconstruction, total/reverse shoulder replacements, arthroscopic elbow surgery, elbow reconstruction and repair including “Tommy John” surgery, arthroscopic knee surgery to include meniscus debridement and/or repair, ligament reconstruction including ACL repair/reconstruction and repair/reconstruction of multi-ligamentous knee injuries, knee cartilage repair/replacement techniques and knee osteotomies for malalignment.

Dr. Mazoué is a member of the American Academy of Orthopaedic Surgeons (AAOS), the American Orthopaedic Society for Sports Medicine (AOSSM), the Southern Orthopaedic Association (SOA) and the South Carolina Orthopaedic Association (SCOA). Dr. Mazoué was elected to the American Orthopedic Association, the oldest orthopedic association in the United States, in June 2018. He has numerous publications and gives lectures locally, regionally and nationally.

“When you typically think of an athlete – you’re thinking high school, college or professional athletes. We treat many of these elite athletes, yet I think sports medicine really extends to the 40- and 50-year-old weekend warriors. It’s those 40-, 50- and 60-year-olds that have goals and ambitions, and we’re trying to allow those people to reach them. My job is to get people back to doing what they love to do.”


Brookland Cayce
Calhoun Academy
Cardinal Newman
Fairfield Central



Education and training

Specialty(s)Orthopedic Surgery, Sports Medicine

Board CertifiedAmerican Board of Orthopaedic Surgery

EducationLouisiana State University School of Medicine

ResidencyUniversity of Texas Southwestern

FellowshipAmerican Sports Medicine Institute

Research and publications
  • Therapeutic ultrasound affects IGF-1 splice variant expression in human skeletal muscle. View »
    Delgado-Diaz DC, Gordon BS, Dompier T, Burgess S, Dumke C, Mazoué C, Caldwell T, Kostek MC
    Am J Sports Med. 2011 Oct;39(10):2233-41. doi: 10.1177/0363546511414857. Epub 2011 Jul 22.
  • Repair of full-thickness rotator cuff tears in professional baseball players. View »
    Mazoué CG, Andrews JR
    Am J Sports Med. 2006 Feb;34(2):182-9. Epub 2005 Oct 31.
  • Arthroscopic management of tibial plateau fractures: an unselected series. View »
    Mazoue CG, Guanche CA, Vrahas MS
    Am J Orthop (Belle Mead NJ). 1999 Sep;28(9):508-15.
  • Injuries to the shoulder in athletes. View »
    Mazoué CG, Andrews JR
    South Med J. 2004 Aug;97(8):748-54. Review.

Research and Publications

Treatments and services

Head and neck:

  • Sports concussions


  • Cartilage transplantation
  • Collateral ligament sprains
  • Iliotibial band friction syndrome and greater trochanteric bursitis
  • Jumper's knee (patellar tendonitis)
  • Meniscal injuries
  • Multiple ligament injury repair
  • Osgood-Schlatter disease
  • Osteoarthritis of the knee
  • Osteochondral injuries
  • Patellofemoral stress syndrome
  • Posterior cruciate ligament ruptures
  • Anterior cruciate ligament (ACL) injuries
  • Platelet rich plasma (PRP) injections

Lower leg, foot and ankle:

  • Achilles tendonitis
  • Ankle sprains
  • Calcaneal Apophysitis (Sever’s disease)
  • Cartilage transplantation
  • Compartment syndrome
  • Hip labral tear
  • Shin splints
  • Stress fractures in the female athlete
  • Turf toe

Shoulder/arm injuries:

  • Adhesive capsulitis
  • Impingement syndrome
  • Labral (SLAP) tears of the shoulder
  • Lateral epicondylitis (tennis elbow)
  • Scaphoid (navicular) fractures of the hand and wrist
  • Rotator cuff tears
  • Shoulder instability
Professional associations
  • American Academy of Orthopaedic Surgeons
  • American Orthopedic Association
  • American Orthopaedic Society for Sports Medicine
  • South Carolina Orthopaedic Association
  • Southern Orthopaedic Association

Our affiliate system

Prisma Health is the largest not-for-profit health organization in South Carolina, serving more than 1.2 million patients annually. Our 30,000 team members are dedicated to supporting the health and well-being of you and your family. Palmetto Health-USC Medical Group will be rebranded at a later date and will continue to operate as a joint venture between the Midlands affiliate and the USC School of Medicine.

Our promise is to: Inspire health. Serve with compassion. Be the difference.

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Palmetto Health is becoming Prisma Health. Palmetto Health-USC Medical Group is part of Prisma Health.