Matthew G. Cantrell, MD

Cardiovascular Disease


Matthew G. Cantrell, MD, FACC, FSCAI, is a cardiologist with Palmetto Heart and a clinical assistant professor at the University of South Carolina School of Medicine. He earned his undergraduate degree at Miami University in Oxford, Ohio, and his medical degree at the Ohio State University College of Medicine and Public Health in Columbus.

Dr. Cantrell completed his internship and residency in internal medicine at the University of North Carolina Hospitals in Chapel Hill, and completed his fellowship in general cardiology and interventional cardiology at St. Vincent Hospital in Indianapolis, Indiana. He is board certified in internal medicine, cardiovascular disease and interventional cardiology. Dr. Cantrell is co-director of the Valve Center at Palmetto Health Heart Hospital.

Our Vision: To be known for clinical excellence and remembered for compassionate care.


Education and training

Specialty Cardiovascular Disease

Board CertifiedAmerican Board of Internal Medicine

EducationOhio State University College of Medicine

ResidencyUniversity of North Carolina Hospitals

FellowshipSt. Vincent Hospital

Our affiliate system

Prisma Health is the largest not-for-profit health organization in South Carolina, serving more than 1.2 million patients annually. Our 30,000 team members are dedicated to supporting the health and well-being of you and your family. Palmetto Health-USC Medical Group will be rebranded at a later date and will continue to operate as a joint venture between the Midlands affiliate and the USC School of Medicine.

Our promise is to: Inspire health. Serve with compassion. Be the difference.

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We are becoming Prisma Health-USC Medical Group