S. Wendell Holmes, MD

Orthopedic Surgery, Sports Medicine
Clinical Assistant Professor of Orthopedic Surgery


S. Wendell Holmes Jr., MD, received his medical degree from the University of South Carolina School of Medicine in Columbia, where he currently serves as a clinical assistant professor of orthopedic surgery. He completed his internship at Palmetto Health Richland in Columbia and residencies at Palmetto Health Richland and Shriners Hospital for Children in Greenville, South Carolina. He completed an orthopedic sports medicine fellowship at the American Sports Medicine Institute in Birmingham, Alabama, under the direction of James Andrews, MD, and William Clancy, MD. Dr. Holmes is board certified by the American Board of Orthopaedic Surgery.

Prior to entering medical school, Dr. Holmes graduated from Clemson University, in Clemson, South Carolina, with a bachelor's degree in chemical engineering. He then worked as an engineer in the research and development department of Ethyl Corporation, where he performed research resulting in five U.S. patents. He joined Moore Clinic in 1997 and practiced as a sports medicine surgeon for 17 years before joining Palmetto Health-USC Orthopedic Center.

Dr. Holmes currently serves as the co-medical director of sports medicine at Palmetto Health-USC Orthopedic Center. He has served on the Medical Aspects of Sports Committee for the last 20 years and served as chairman for 12 years. He is a great supporter of sports medicine outreac and has been awarded honorary membership to the National Athletic Trainers Association, in addition to receiving the President’s Award from the South Carolina Athletic Trainers Association.

Dr. Holmes is a member of numerous medical associations including the American Orthopaedic Society for Sports Medicine, American Academy of Orthopaedic Surgeons, American Sports Medicine Institute Fellowship Society, South Carolina Orthopaedic Association, and the South Carolina Medical Association.

“Sometimes your sport is football and sometimes it’s getting to the mailbox. We’ll take care of all of those problems because our mission is to give the highest level of care possible to athletes and patients of all ages for both prevention and treatment of injuries.”


Dutch Fork
Gray Collegiate
Newberry College



Education and training

Specialty(s)Orthopedic Surgery, Sports Medicine

Board CertifiedAmerican Board of Orthopaedic Surgery

EducationUniversity of South Carolina School of Medicine

ResidencyPalmetto Health Richland; Shriners Hospital for Children

FellowshipAmerican Sports Medicine Institute

Research and publications
  • Articular cartilage injuries in the athlete's knee: current concepts in diagnosis and treatment. View »
    Holmes SW Jr.
    South Med J. 2004 Aug;97(8):742-7. Review. No abstract available.
  • Clinical classification of patellofemoral pain and dysfunction. View »
    Holmes SW Jr, Clancy WG Jr.
    J Orthop Sports Phys Ther. 1998 Nov;28(5):299-306.

Research and Publications

Treatments and services
  • Sports medicine
  • Shoulder and knee arthroscopy
  • Arthroscopic ACL reconstruction
  • Arthroscopic rotator cuff repair
  • Arthroscopic superior capsular reconstruction (SCR)
  • Arthroscopic shoulder stabilization
  • Cartilage replacement/repair techniques (Carticel, OATS)
  • Meniscus repair and reconstruction
  • Meniscus transplantation
  • Elbow arthroscopy
  • Elbow reconstruction
  • Tommy John UCL reconstruction
  • Total shoulder reconstruction
Professional associations
  • American Academy of Orthopaedic Surgeons
  • American Orthopaedic Society for Sports Medicine
  • American Sports Medicine Institute Fellowship Society
  • South Carolina Medical Association
  • South Carolina Orthopaedic Association

Our affiliate system

Prisma Health is the largest not-for-profit health organization in South Carolina, serving more than 1.2 million patients annually. Our 30,000 team members are dedicated to supporting the health and well-being of you and your family. Palmetto Health-USC Medical Group will be rebranded at a later date and will continue to operate as a joint venture between the Midlands affiliate and the USC School of Medicine.

Our promise is to: Inspire health. Serve with compassion. Be the difference.

Learn More
Palmetto Health is becoming Prisma Health. Palmetto Health-USC Medical Group is part of Prisma Health.