T. Fleming Mattox, MD

Obstetrics and Gynecology


Thomas Fleming Mattox, MD, received his medical degree from the University of North Carolina in Chapel Hill and completed his residency at Louisana State University School of Medicine/Charity Hospital in New Orleans.

Dr. Mattox was one of the first board-certified and fellowship-trained urogynecologists in South Carolina and has been affiliated with the Department of Obstetrics and Gynecology at the University of South Carolina School of Medicine in Columbia since 1997.

He specializes in pelvic floor disorders including urinary incontinence, pelvic organ prolapse and bladder pain, and is an accomplished surgeon, performing over 1000 minimally invasive laparoscopic pelvic suspensions and more than 2000 minimally invasive sub-urethral slings. He is an expert in treating vaginal mesh complications, is widely published and is a nationally recognized speaker. He has been awarded the CREOG award for excellence in teaching.

Our Vision: To be known for clinical excellence and remembered for compassionate care.


Education and training

Specialty Obstetrics and Gynecology

Board CertifiedAmerican Board of Obstetrics and Gynecology

EducationUniversity of North Carolina

ResidencyLouisiana State University School of Medicine

FellowshipHarbor - UCLA Medical Center

Our affiliate system

We are building one organization with affiliates in two regions. Our parent company, now known as Prisma Health, supports both affiliates with overall direction and leadership as we continue to align. We will soon share one brand across the entire organization to better reflect this. Palmetto Health-USC Medical Group will be rebranded in late 2019 and will continue to operate as a joint venture between the Midlands affiliate and the USC School of Medicine.

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We are becoming Prisma Health-USC Medical Group